Dedicator of cytokinesis 8–deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells
Year: 2016
Type: article
Study design: Observational Study
Authors: Stuart G. Tangye, Bethany Pillay, Katrina L. Randall, Danielle T. Avery, Tri Giang Phan, Paul Gray, John B. Ziegler, Joanne M. Smart, Jane Peake, Peter D. Arkwright, Sophie Hambleton, Jordan Orange, Christopher C. Goodnow, Gulbu Uzel, Jean-Laurent Casanova, Saul Oswaldo Lugo Reyes, Alexandra F. Freeman, Helen C. Su, Cindy S. Ma
Institutions: Garvan Institute of Medical Research, UNSW Sydney, Australian National University, Royal Children's Hospital, The University of Queensland, Children's Health Queensland Hospital and Health Service, University of Manchester, Royal Manchester Children's Hospital, Great North Children's Hospital, Newcastle University, Baylor College of Medicine, Texas Children's Hospital, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Hôpital Necker-Enfants Malades, Howard Hughes Medical Institute, Inserm, Assistance Publique – Hôpitaux de Paris, Institut des Maladies Génétiques Imagine, Université Paris Descartes, Rockefeller University, Instituto Nacional de Pediatria
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Awards: Understanding T-cell dependent B-cell responses, Transforming Translational Science and Education to Benefit Human Health, Uncovering the basis of inflammatory and immunodeficiency diseases, Investigating DOCK8 immunodeficiency, Utilising human immunodeficiencies to study the immune system, Determining the role of DOCK8 in CD4+ T and B cell differentiation and its implications on autosomal recessive hyper IgE syndrome (AR-HIES), G606335999, Defining the requirements for effective immune responses, Understanding DOCK8 Function in Health and Human Disease
OpenAlex ID: W2512898954