Population-Based Precision Cancer Screening: A Symposium on Evidence, Epidemiology, and Next Steps
Year: 2016
Type: article
Abstract: Precision medicine, an emerging approach for disease treatment that takes into account individual variability in genes, environment, and lifestyle, is under consideration for preventive interventions, including cancer screening. On September 29, 2015, the National Cancer Institute sponsored a symposium entitled "Precision Cancer Screening in the General Population: Evidence, Epidemiology, and Next Steps". The goal was two-fold: to share current information on the evidence, practices, and challenges surrounding precision screening for breast, cervical, colorectal, lung, and prostate cancers, and to allow for in-depth discussion among experts in relevant fields regarding how epidemiology and other population sciences can be used to generate evidence to inform precision screening strategies. Attendees concluded that the strength of evidence for efficacy and effectiveness of precision strategies varies by cancer site, that no one research strategy or methodology would be able or appropriate to address the many knowledge gaps in precision screening, and that issues surrounding implementation must be researched as well. Additional discussion needs to occur to identify the high priority research areas in precision cancer screening for pertinent organs and to gather the necessary evidence to determine whether further implementation of precision cancer screening strategies in the general population would be feasible and beneficial. Cancer Epidemiol Biomarkers Prev; 25(11); 1449-55. ©2016 AACR.
Authors: Pamela M. Marcus, Nora Pashayan, Timothy R. Church, V. Paul Doria-Rose, Michael K. Gould, Rebecca A. Hubbard, Michael Marrone, Diana L. Miglioretti, Paul D. Pharoah, Paul F. Pinsky, Katherine A. Rendle, Hilary A. Robbins, Megan C. Roberts, Betsy Rolland, Mark Schiffman, Jasmin A. Tiro, Ann G. Zauber, Deborah M. Winn, Muin J. Khoury
Institutions: National Cancer Institute, University College London, University of Minnesota, Kaiser Permanente, University of Pennsylvania, Johns Hopkins University, University of California, Davis, University of Cambridge, University of Wisconsin–Madison, University of Wisconsin Carbone Cancer Center, Division of Cancer Epidemiology and Genetics, The University of Texas Southwestern Medical Center, Memorial Sloan Kettering Cancer Center, Centers for Disease Control and Prevention, Office of Public Health Genomics
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2514971305