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Fluorescence-based assay for polyprenyl phosphate-GlcNAc-1-phosphate transferase (WecA) and identification of novel antimycobacterial WecA inhibitors

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Year: 2016
Type: article
Source: Analytical Biochemistry
DOI: 10.1016/j.ab.2016.08.008
Authors: Katsuhiko Mitachi, Shajila Siricilla, Dong Yang, Ying Kong, Karolina Skorupinska-Tudek, Ewa Swiezewska, Scott G. Franzblau, Michio Kurosu
Institutions: University of Tennessee Health Science Center, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Polish Academy of Sciences, University of Illinois Chicago
Language: English

Topic: Tuberculosis Research and Epidemiology
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: University of Tennessee, National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases
Awards: Targeting MraY: Synthesis and Validation of MraY Inhibitors, Mechanistic details of key integral membrane enzymes for antimicrobial discovery
OpenAlex ID: W2515832379
FWCI: 3.694
Cites: 65
Cited by: 32
Related to: 10
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