Year: 1983
Type: article
Abstract: The reaction of γ, δ- or δ, ε-unsaturated carboxylic acid with halogen afford halolactone in high yield. This halolactonization reaction generally proceeds in a high stereo- and regiospecific manner. This makes the reaction one of the most important procedures for the functionalization of the carbon-carbon double bond.This review provides illustrative examples of the synthesis of natural products where halolactonization reaction plays an important role.Some related reactions are also described.
Author: Susumu KOBAYASHI
Institution: The University of Tokyo
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W2516495408