Relationship between vitamin D receptor gene polymorphisms and alcoholic liver disease
Year: 2009
Type: article
Abstract: 目的:探讨维生素D受体(vitamin Dreceptor VDR)基因多态性与酒精性肝病易感性之间的关系.方法:采用半巢式聚合酶链式反应-限制性片段长度多态性(semi-nested PCR-RFLP)技术检测50例酒精性肝病患者和72例健康志愿者VDR多态性的基因型,并比较甘肃汉族人群和酒精性肝病患者之间VDR基因多态性、基因型频率、等位基因频率的差异与酒精性肝病相关性的分析.结果:共检出3种VDR基因型,即BB、Bb、bb.病例组bb基因型频率显著高于对照组(χ2=7.16,P=0.028,OR=2.698,95%CI1.167-6.235);b等位基因的频率病例组显著高于对照组(χ2=...
Language: English
Topic: Vitamin D Research Studies
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2517454261