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Synthesis, evaluation, and CoMFA study of fluoroquinophenoxazine derivatives as bacterial topoisomerase IA inhibitors

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Year: 2016
Type: article
Source: European Journal of Medicinal Chemistry
DOI: 10.1016/j.ejmech.2016.09.053
Authors: Xufen Yu, Mingming Zhang, Thirunavukkarasu Annamalai, Priyanka Bansod, Gagandeep Narula, Yuk-Ching Tse-Dinh, Dianqing Sun
Institutions: University of Hawaii at Hilo, Florida International University
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, University of Illinois at Urbana-Champaign, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Center for Research Resources
Awards: Development of Piperidinols and Engelhardiones as Novel Antituberculosis Agents, Bacterial cell killing by topoisomerase I mediated DNA lesion, INBRE II: Hawaii Statewide Research & Education Partnership (HSREP), HAWAII INBRE V PROGRAM
OpenAlex ID: W2518684392
FWCI: 1.559
Cites: 31
Cited by: 23
Related to: 10
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