Work

Effect of Usnic Acid on Candida orthopsilosis and C. parapsilosis

Year: 2011

Type: article

Abstract: The activity of usnic acid against Candida orthopsilosis and Candida parapsilosis on planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potent in vitro activities against different Candida species were obtained. The metabolic activity of sessile cells of C. parapsilosis complex was reduced by 80% at four times the 80% inhibitory concentration. The in vitro studies support further efforts to determine whether usnic acid can be used clinically to cure patients with Candida infections.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.05348-11

Authors: Regina Helena Pires, Rodrigo Lucarini, Maria Jose Soares Mendes-Giannini

Institutions: Universidade Estadual Paulista (Unesp), Universidade de Franca

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2150053643