Whole exome sequencing in families with CLL detects a variant in Integrin β 2 associated with disease susceptibility
Year: 2016
Type: article
Abstract: To the editor:
Chronic lymphocytic leukemia (CLL) is one of the most common B-cell malignancies in individuals of European ancestry in the United States.[1][1] Although advanced age, white ancestry, and family history of hematologic malignancies are risk factors, the etiology of CLL is unknown.[2][
Source: Blood
Authors: Lynn R. Goldin, Mary L. McMaster, Melissa Rotunno, Sarah E. M. Herman, Kristine Jones, Bin Zhu, Joseph Boland, Laurie Burdett, Belynda Hicks, Sarangan Ravichandran, Brian T. Luke, Meredith Yeager, Laura Fontaine, Alisa M. Goldstein, Stephen J. Chanock, Margaret A. Tucker, Adrian Wiestner, Gerald Marti, Neil E. Caporaso
Institutions: Division of Cancer Epidemiology and Genetics, National Institutes of Health, National Cancer Institute, National Heart, Lung, and Blood Institute, Frederick National Laboratory for Cancer Research, Westat (United States), United States Food and Drug Administration, Center for Devices and Radiological Health
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: National Cancer Institute
Award: G386607036
OpenAlex ID: W2520601012