Work

Multiobjective guided priors improve the accuracy of near-infrared spectral tomography for breast imaging

Year: 2016

Type: article

Abstract: An image reconstruction regularization approach for magnetic resonance imaging-guided near-infrared spectral tomography has been developed to improve quantification of total hemoglobin (HbT) and water. By combining prior information from dynamic contrast enhanced (DCE) and diffusion weighted (DW) MR images, the absolute bias errors of HbT and water in the tumor were reduced by 22% and 18%, 21% and 6%, and 10% and 11%, compared to that in the no-prior, DCE- or DW-guided reconstructed images in three-dimensional simulations, respectively. In addition, the apparent contrast values of HbT and water were increased in patient image reconstruction from 1.4 and 1.4 (DCE) or 1.8 and 1.4 (DW) to 4.6 and 1.6.

Source: Journal of Biomedical Optics

DOI: 10.1117/1.jbo.21.9.090506

Authors: Jinchao Feng, Shudong Jiang, Junqing Xu, Yan Zhao, Brian W. Pogue, Keith D. Paulsen

Institutions: Dartmouth College, Beijing University of Technology, Xijing Hospital

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,675