Year: 2016
Type: article
Abstract: Studies concerning the gut microbiota have exponentially increased since the 1970s. A healthy gut microbiota is essential for growth and weight gain in infants as well as for a thorough harvest of energy from diet through a role in digestion. Study techniques include culture-independent and culture-dependent methods aiming at describing the gut microbiota taxonomically and functionally. Healthy gut microbiota plays a role in digestion by metabolizing indigestible macronutrients resulting in short chain fatty acids and other bioactive compounds. Diet was proven to influence the composition of the gut microbiota with specific changes to the major macronutrient contained in the diet. Since diet has an influence on gut microbiota’s composition, nutritional disorders such as obesity, severe acute malnutrition and anorexia nervosa are linked to an alteration of the gut microbiota mirroring the physiopathology of the nutritional disorder. These alterations should be the target of future therapeutic interventions in nutritional disorders.
Source: Human Microbiome Journal
Institutions: Centre National de la Recherche Scientifique, Aix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, Institut de Recherche pour le Développement, Institut de Recherche pour le Développement, Cheikh Anta Diop University, King Abdulaziz University
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $2,400
Funder: Fondation Méditerranée Infection
OpenAlex ID: W2522316027