Year: 2016
Type: article
Study design: Observational Study
Abstract: There is a growing interest in understanding the role of inflammation in diet-depression relationship. The present study examined whether the dietary inflammatory index (DII, a measure of the inflammatory potential of individuals' diets) is associated with recurrent depressive symptoms (DepS) (CES-D score>16 or taking antidepressants both at baseline and follow-up) assessed over 5 years in middle-aged men (n=3178) and women (n=1068) from the Whitehall II Study. For each increment of 1 SD of DII score, odds of recurrent DepS increased by 66% (95 % CI:1.30-2.12) in women while no significant association between DII and recurrent DepS was observed in men (OR=1.12, 95 % CI: 0.92-1.36). This association was little attenuated after adjustment for confounders and after taking into account levels of interleukin-6 and C-reactive protein. In conclusion, there is an association between pro-inflammatory diet and recurrent DepS in women which seems not be driven by circulating inflammatory markers.
Source: Clinical Psychological Science
Authors: Tasnime N. Akbaraly, Clarisse Kerleau, Marilyn Wyart, Nathalie Chevallier, Louise Ndiaye, Nitin Shivappa, James R. Hébert, Mika Kivimäki
Language: English
Topic: Nutritional Studies and Diet
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: Health behaviors over the adult lifecourse and cognitive aging, Developing the Dietary Inflammatory Index for Clinical Application, Longitudinal assessment of aortic stiffness in the Whitehall II study. ,, Vascular risk and functional decline in old age (renewal), Socio-economic status and heterogeneity in aging, Socioeconomic gradient in CHD in early old age
OpenAlex ID: W2527255327