Work

Cellular and Molecular Imaging Using Chemical Exchange Saturation Transfer

Year: 2016

Type: review

Abstract: Chemical exchange saturation transfer (CEST) is a powerful new tool well suited for molecular imaging. This technology enables the detection of low concentration probes through selective labeling of rapidly exchanging protons or other spins on the probes. In this review, we will highlight the unique features of CEST imaging technology and describe the different types of CEST agents that are suited for molecular imaging studies, including CEST theranostic agents, CEST reporter genes, and CEST environmental sensors.

Source: Topics in Magnetic Resonance Imaging

DOI: 10.1097/rmr.0000000000000105

Authors: Michael T. McMahon, Assaf A. Gilad

Institutions: Kennedy Krieger Institute, Johns Hopkins University, Johns Hopkins Medicine

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of Biomedical Imaging and Bioengineering

Award: Multi-Color Exchange Transfer Imaging of Drug Delivery Nanocarriers