Allergic asthma is distinguished by sensitivity of allergen-specific CD4 + T cells and airway structural cells to type 2 inflammation
Year: 2016
Type: article
Abstract: The development of allergic asthma requires type 2 airway inflammation as well as increased sensitivity of airway epithelial cells and smooth muscle to inflammation.
Source: Science Translational Medicine
Authors: Josalyn L. Cho, Morris F. Ling, David C. Adams, Lucas Faustino, Sabina A. Islam, Roshi Afshar, Jason W. Griffith, Robert S. Harris, Aylwin Ng, Giorgia Radicioni, Amina A. Ford, Andre K. Han, Ramnik Xavier, William W. Kwok, Richard Boucher, James J. Moon, Daniel L. Hamilos, Mehmet Kesimer, Melissa J. Suter, Benjamin D. Medoff, Andrew D. Luster
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Increasing the diagnostic yield of low-risk bronchial biopsy in the evaluation of, The role of mucin-protein interactions in the innate defense of the lung, Airway mucus/mucin composition and proteome in COPD: A SPIROMICS ancillary study, T cell effector and regulatory mechanisms in asthma and food allergy, Tim3 is a novel regulator of dendritic cell-T cell interactions in influenza, Chemokines and Th2 Cell Trafficking in Asthma, Modulation of chronic Th2 inflammation by the CCR8 receptor-ligand pathway, Harvard Clinical and Translational Science Center, Research Training in Pulmonary Immunology and Allergy at Massachusetts General Hospital, Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital
OpenAlex ID: W2529381683