Work

Genistein Induces Apoptosis and Inhibits Proliferation of HT29 Colon Cancer Cells.

Year: 2016

Type: article

Abstract: gene expression and its active phosphorylated protein level. Also, we showed that genistein strongly suppressed the metastatic potency of HT29 colon cancer cells via the reduction of MMP2 activity. Based on the results of this study, we conclude that genistein may exhibit its anticancer properties on HT29 colon cancer cells by modulating caspase-3 and p38 MAPK pathway at different transcriptional and protein levels.

Source: Europe PMC (PubMed Central)

Authors: Gholamreza Shafiee, Massoud Saidijam, Heidar Tavilani, Neda Ghasemkhani, Iraj Khodadadi

Institution: Hamedan University of Medical Sciences

Language: English

Topic: Phytoestrogen effects and research

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2529945898

FWCI: 6.367

Cites: 40

Cited by: 79

Related to: 10