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An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers

Year: 2016
Type: article
Source: Cancer Cell
DOI: 10.1016/j.ccell.2016.09.008
Authors: Genaro R. Villa, Jonathan J. Hulce, Ciro Zanca, Junfeng Bi, Shiro Ikegami, Gabrielle L. Cahill, Yuchao Gu, Kenneth M. Lum, Kenta Masui, Huijun Yang, Xin Rong, Cynthia Hong, Kristen M. Turner, Feng Liu, Gary C. Hon, David Jenkins, Michael Martini, Aaron M. Armando, Oswald Quehenberger, Timothy F. Cloughesy, Frank B. Furnari, Webster K. Cavenee, Peter Tontonoz, Timothy C. Gahman, Andrew K. Shiau, Benjamin F. Cravatt, Paul S. Mischel
Institutions: University of California, Los Angeles, University of California San Diego, Scripps Research Institute, Tokyo Women's Medical University, Moores Cancer Center, Howard Hughes Medical Institute
Language: English
Subfield: Cancer Research
Open Access status: bronze
Funders: National Brain Tumor Society, Ben and Catherine Ivy Foundation, Ziering Family Foundation, National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke
Awards: The role of mTORC2 in reprogramming cancer cell metabolism, Genotypic Interactions in Brain Cancer Heterogeneity, Genotypic Interactions in Brain Cancer Heterogeneity, G4791736148, A Novel Approach to Treating Glioblastoma through Activation of the Liver X Recep, G9000153503
OpenAlex ID: W2530768869
FWCI: 8.973
Cites: 59
Cited by: 325
Related to: 10