Work

Data on microRNAs and microRNA-targeted mRNAs in Xenopus ectoderm

Year: 2016

Type: data-paper

Abstract: Small RNAs from early neural (i.e., Noggin-expressing, or NOG) and epidermal (expressing a constitutively active BMP4 receptor, CABR) ectoderm in Xenopus laevis were sequenced to identify microRNAs (miRs) expressed in each tissue. Argonaute-associated mRNAs were isolated and sequenced to identify genes that are regulated by microRNAs in these tissues. Interactions between these ectodermal miRs and selected miR-regulated mRNAs were predicted using the PITA algorithm; PITA predictions for over 600 mRNAs are presented. All sequencing data are available at NCBI (NCBI Bioproject Accession number: PRJNA325834). This article accompanies the manuscript “MicroRNAs and ectodermal specification I. Identification of miRs and miR-targeted mRNAs in early anterior neural and epidermal ectoderm” (V.V. Shah, B. Soibam, R.A. Ritter, A. Benham, J. Oomen, A.K. Sater, 2016) [1].

Source: Data in Brief

DOI: 10.1016/j.dib.2016.09.054

Authors: Vrutant V. Shah, Benjamin Soibam, Ruth A. Ritter, Ashley Benham, Jamina Oomen, Amy K. Sater

Institutions: University of Houston, University of Houston - Downtown, Stony Brook University

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,220

Funders: National Science Foundation, University of Houston, University of Texas at Austin