Development of Auto Antigen-specific Regulatory T Cells for Diabetes Immunotherapy
Year: 2016
Type: review
Abstract: , islets) to suppress autoimmune responses after adoptive transfer, thereby avoiding potential overall immunosuppression from non-specific Tregs. Developing auto Ag-specific PSC-Tregs can reduce overall immunosuppression after adoptive transfer by accumulating inflamed islets, which drives forward the use of therapeutic PSC-Tregs for cell-based therapies in T1D.
Source: Immune Network
Author: Jianxun Song
Institution: Pennsylvania State University
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: hybrid
Awards: Directed differentiation of HBV-specific CTL from iPSC for cell-based therapies, Impact of Highly Active T Lymphocytes from Induced Pluripotent Stem Cells, Role of stem cell-derived T lymphocytes in chronic HBV infection, G4205787609, Stem cell-derived regulatory T cells for therapeutic use in arthritis
OpenAlex ID: W2540347122