Efeitos da suplementação de glutamina sobre o sistema imune em atletas submetidos ao treinamento excessivo: uma revisão sistemática
Year: 2016
Type: article
Study design: Systematic Review
Abstract: Effects of glutamine supplementation on the immune system in athletes subjected to overtraining: a systematic reviewThe current study aims to evaluate the effects of glutamine supplementation on the immunological changes induced by overtraining in athletes. A systematic review was performed on PubMed, Bireme and Scopus databases, using the keywords “glutamine”, “overtraining”, ”athletes” and the Boolean operator “and”. Only articles published between the years of 1990 and 2015 in multiple languages were included. The pre-selected articles were submitted to the Jadad scale to evaluate the methodological quality of the studies and three reviewers were recruited to perform the article search in order to avoid selection bias. After application of the inclusion and exclusion criteria, 4 studies were considered for this review. All the selected articles had a score >_3 on Jadad scale, which implies good methodological quality. The evaluated studies performed short duration and had participants with different characteristics, including differences in the type of sport practiced, the participant’s age and glutamine supplementation dose. In conclusion, there appears to be sufficient data demonstrating the influence of intense physical exercise on plasma glutamine concentration however there are controversies relating to the positive effects of glutamine intake on immunological parameters of athletes subjected to strenuous exercises. Therefore, further studies investigating long-term glutamine supplementation are necessary in order to confirm the real effects of this supplementation in improved immunity in athletes subjected to excessive training.
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2540915799