Work

Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library

Year: 2016

Type: article

Source: Nature Biotechnology

DOI: 10.1038/nbt.3715

Authors: Shiyou Zhu, Wei Li, Jingze Liu, Chen-Hao Chen, Qi Liao, Ping Xu, Han Xu, Tengfei Xiao, Zhongzheng Cao, Jingyu Peng, Pengfei Yuan, Myles Brown, Xiaole Shirley Liu, Wensheng Wei

Institutions: Peking University, Center for Life Sciences, State Key Laboratory of Protein and Plant Gene Research, Tsinghua University, Harvard University, Dana-Farber Cancer Institute, Ningbo University, Broad Institute, Massachusetts Institute of Technology, Brigham and Women's Hospital

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Human Genome Research Institute, National Cancer Institute

Awards: Large-Scale In Vivo Functional Characterization of the Human Cistrome, Developing Informatics Technologies to Model Cancer Gene Regulation

OpenAlex ID: W2544093984

FWCI: 24.53

Cites: 52

Cited by: 425

Related to: 10