Work

Copper( ii )-doped semiconducting polymer dots for nitroxyl imaging in live cells

Year: 2016

Type: article

Abstract: The first nanoparticle-based fluorescent probe for the specific detection of nitroxyl (HNO) was designed and constructed by doping copper(II) into semiconducting polymer dots (Pdots). The probe turns on and fluoresces in the presence of HNO. We used the new sensor to monitor changes of HNO levels in live cells.

Source: RSC Advances

DOI: 10.1039/c6ra20439b

Authors: Xu Wu, Li Wu, I.-Che Wu, Daniel T. Chiu

Institution: University of Washington

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute

Award: Ultra-Bright Probes with Ultra-Narrow Emission for Molecular and Cellular Analysi