Work

A Case of Lipid Core Plaque Progression and Rupture at the Edge of a Coronary Stent

Year: 2010

Type: article

Abstract: U nderstanding the mechanisms of coronary drug-eluting stent (DES) failure remains relevant in light of concerns brought on by clinical reports of life-threatening late and very late stent thrombosis and by autopsy studies showing delayed and incomplete healing inside the stents, which may be related to underlying necrotic lipid core. 1 Frequency-domain optical coherence tomography, also known as optical frequency-domain imaging (OFDI), is a new intracoronary imaging technology that enables 3-dimensional visualization of coronary structure in vivo at a resolution (Ϸ6 m) sufficient to identify many microscopic features of the coronary wall and stents. 2 Here, we present a case of late DES failure that was imaged by OFDI at the time of stent implantation and 15 months later on presentation with unstable angina.The patient was a 52-year-old man with hypertension, dyslipidemia, a family history of coronary artery disease, and prior myocardial infarction in 1998.The patient

Source: Circulation Cardiovascular Interventions

DOI: 10.1161/circinterventions.109.917955