Year: 2016
Type: article
Abstract: Cancer is the leading cause of death in older adults aged 60 to 79 years. Older patients with good performance status are able to tolerate commonly used treatment modalities as well as younger patients, particularly when adequate supportive care is provided. For older patients who are able to tolerate curative treatment, options include surgery, radiation therapy (RT), chemotherapy, and targeted therapies. RT can be highly effective and well tolerated in carefully selected patients, and advanced age alone should not preclude the use of RT in older patients with cancer. Judicious application of advanced RT techniques that facilitate normal tissue sparing and reduce RT doses to organs at risk are important for all patients, and may help to assuage concerns about the risks of RT in older adults. These NCCN Guidelines Insights focus on the recent updates to the 2016 NCCN Guidelines for Older Adult Oncology specific to the use of RT in the management of older adults with cancer.
Authors: Noam VanderWalde, Reshma Jagsi, Efrat Dotan, Joel Baumgartner, Ilene S. Browner, Peggy Burhenn, Harvey Jay Cohen, Barish H. Edil, Beatrice Edwards, Martine Extermann, Apar Kishor P. Ganti, Cary Gross, Joleen Hubbard, Nancy L. Keating, Beatriz Korc-Grodzicki, June M. McKoy, Bruno C. Medeiros, Ewa Mrozek, Tracey O'Connor, Hope S. Rugo, Randall W. Rupper, Dale Shepard, Rebecca A. Silliman, Derek L. Stirewalt, William P. Tew, Louise C. Walter, Tanya Wildes, Mary Anne Bergman, Hema Sundar, Arti Hurria
Institutions: Northwestern University, St. Jude Children's Research Hospital, Mayo Clinic, The University of Texas MD Anderson Cancer Center, University of Tennessee Health Science Center, University of Colorado Cancer Center, Dana-Farber Brigham Cancer Center, University of Michigan, U-M Rogel Cancer Center, Fox Chase Cancer Center, Moores Cancer Center, Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center, City Of Hope National Medical Center, City of Hope, Duke Cancer Institute, Moffitt Cancer Center, Fred and Pamela Buffett Cancer Center, Yale Cancer Center, Smilow Cancer Hospital, Mayo Clinic Comprehensive Cancer Center (Minnesota), Memorial Sloan Kettering Cancer Center, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Stanford Cancer Institute, Roswell Park Comprehensive Cancer Center, The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, UCSF Helen Diller Family Comprehensive Cancer Center, Huntsman Cancer Institute, Cleveland Clinic, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Seattle Cancer Care Alliance, Fred Hutch Cancer Center, Barnes-Jewish Hospital, National Comprehensive Cancer Network
Language: English
Topic: Frailty in Older Adults
Subfield: Geriatrics and Gerontology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2548545261