Mechanisms of Mycobacterial Transmission: How does Mycobacterium Tuberculosis enter and Escape from the Human Host
Year: 2016
Type: editorial
Abstract: In 1882, while lecturing on his discovery of the cause of tuberculosis, Robert Koch said "If the importance of a disease for mankind is measured by the number of fatalities it causes, then tuberculosis must be considered much more important than those most feared infectious diseases, plague, cholera and the like."Although Koch's identification of Mycobacterium tuberculosis (Mtb) as the cause of tuberculosis heralded many future discoveries and treatments, Mtb remains responsible for 1.5 million deaths annually.Therefore, more research is needed on all stages of Mtb infection.This commentary provides a framework for understanding two central questions in Mtb biology at the extremes of the infectious life cycle: how does Mtb enter the body and how does it escape?
Source: Future Microbiology
Author: Michael U Shiloh
Institution: The University of Texas Southwestern Medical Center
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2550538007