Antioxidants in Health and Disease: Review of Clinical Trials
Year: 2013
Type: article
Abstract: Mortality and morbidity associated with cancer is a major public health problem.It was estimated that 12.7 million people were affected by cancer worldwide in 2008 8 .Furthermore, about 7.6 million deaths were attributed to cancer 8 .Breast cancer and lung cancer are the leading causes of cancer death among females and males, respectively 8 .The development of cancer is a multistage process that involves initiation, progression Abstract Free radicals play an important role in several biological processes such as cell signaling and redox regulation.However, prolonged exposure to free radicals leads to oxidative damage.Subsequently, it has been implicated in the progression of several diseases like cancer, cardiovascular disease, neurological disease, pulmonary disease, rheumatoid arthritis, nephropathy, ocular disease and pre-eclampsia.The antioxidant defense system within the body may confer protection to oxidative damage by scavenging free radicals.Antioxidants also may be obtained from dietary sources/ supplements.The efficacy of antioxidant intake on initiation and progression of chronic diseases will be reviewed.
Author: Namrata Sanjeevi
Language: English
Subfield: Biochemistry (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4250340915