Work

Concept of Phase Cycling in Pulsed Magnetic Resonance Using Sinusoidal Magnetic Field Modulation

Year: 2016

Type: article

Abstract: In conventional pulsed magnetic resonance suppression of unwanted signals is achieved by changing pulse phases with respect to the reference signal and spin magnetization phase. This method is called phase cycling. An alternative approach is suggested to separate the unwanted signals from the spin echo by using magnetic field modulation. Precession frequency of the spins, and therefore phases of free indication decays and echo signals, can be controlled by the selection of modulation parameters. This enables phase cycling. Since the signal is detected in the presence of the changing magnetic field, which drives spin precession, the echo signal is frequency-modulated. Numerical transformation into an accelerating reference frame associated with the Larmor frequency restores the signal to a form that would have been observed in the absence of modulation. The suggested phase cycling method is analyzed in detail for the two pulse spin echo case.

Source: Zeitschrift für Physikalische Chemie

DOI: 10.1515/zpch-2016-0843

Author: Mark Tseytlin

Institutions: West Virginia University, University of Chicago

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Biomedical Imaging and Bioengineering

Awards: G1739031488, Enhancing in vivo EPR imaging using spin probes with short relaxation times, Multifunctional in Vivo EPR Imaging of Tumor Microenvironment, West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health