Work

Visualizing Local Protein Synthesis and Its Modulation by FMRP and Visual Experience

Year: 2016

Type: article

Abstract: Protein synthesis is required to support long-term experience-dependent changes in behavior ([Flexner et al., 1963][1]). Synaptic activity recruits transcriptional and translational machinery that alters gene expression, supporting long-term synaptic plasticity and structural remodeling necessary

Source: Journal of Neuroscience

DOI: 10.1523/jneurosci.2803-16.2016

Authors: Gervasio Batista, Hannah R. Monday

Institution: Albert Einstein College of Medicine

Language: English

Topic: Genetics and Neurodevelopmental Disorders

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: National Institutes of Health, National Institute of Mental Health, National Institute on Drug Abuse, National Institute on Deafness and Other Communication Disorders

Awards: Presynaptic forms of long-term plasticity in the CNS, Activity-dependent synaptic plasticity expressed by NMDARs, Coding of auditory space in the avian brain