Magnetic Nanoparticles for Precision Oncology: Theranostic Magnetic Iron Oxide Nanoparticles for Image-Guided and Targeted Cancer Therapy
Year: 2016
Type: review
Abstract: Recent advances in the development of magnetic nanoparticles (MNPs) have shown promise in the development of new personalized therapeutic approaches for clinical management of cancer patients. The unique physicochemical properties of MNPs endow them with novel multifunctional capabilities for imaging, drug delivery and therapy, which are referred to as theranostics. To facilitate the translation of those theranostic MNPs into clinical applications, extensive efforts have been made on designing and improving biocompatibility, stability, safety, drug-loading ability, targeted delivery, imaging signal and thermal- or photodynamic response. In this review, we provide an overview of the physicochemical properties, toxicity and theranostic applications of MNPs with a focus on magnetic iron oxide nanoparticles.
Source: Nanomedicine
Authors: Lei Zhu, Zhiyang Zhou, Hui Mao, Lily Yang
Institutions: Emory University, Central South University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
Awards: MRI Capable Receptor Targeted Drug Delivery for Pancreatic Cancer, G318930586, Stroma Breaking Theranostic Nanoparticle for Targeted Pancreatic Cancer Therapy, Theranostic Nano particles for Targeted Treatment of Pancreatic Cancer, Targeted Therapy of Triple Negative Breast Cancer Using Theranostic Nanoparticles
OpenAlex ID: W2553579136