Work

Relevance of epithelial-to-pericyte transition in cancer

Year: 2016

Type: article

Abstract: The relevance of epithelial-to-mesenchymal transition (EMT) in cancer is still under debate. Recently, we reported that EMT bestows key pericyte properties on cancer cells and may thus represent epithelial-to-pericyte transition (EPT). Carcinoma cells undergo EPT to stabilize blood vessels and fuel primary tumor growth. Association of EPT cancer cells with vascular niches may also promote resistance to therapy.

Source: Molecular & Cellular Oncology

DOI: 10.1080/23723556.2016.1260672

Authors: Anitha K. Shenoy, Jianrong Lu

Institutions: California Health Sciences University, University of Florida Health, University of Florida

Language: English

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,590