Work

Are healthy smokers really healthy?

Year: 2016
Type: article
Abstract: Cigarette smoke contains more than 4500 chemicals which have toxic, mutagenic and carcinogenic effects. Strong evidences have shown that current smokers take a significantly higher risk of cardiovascular diseases, chronic obstructive pulmonary disease (COPD) and lung cancer than nonsmokers. However, less attention has been paid to the smoking induced abnormalities in the individuals defined as healthy smokers who are normal with spirometry, radiographic images, routine physical exam and categorized as healthy control group in many researches. Actually, 'healthy smokers' are not healthy. This narrative review focuses on the smoking related pathophysiologic changes mainly in the respiratory system of healthy smokers, including inflammation and immune changes, genetic alterations, structural changes and pulmonary dysfunction.
Language: English
Subfield: Physiology
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,372
OpenAlex ID: W2556939010
FWCI: 2.051
Cites: 153
Cited by: 92
Related to: 10