Work

Developmental programming: the role of growth hormone

Year: 2015
Type: article
Abstract: Developmental programming of the fetus has consequences for physiologic responses in the offspring as an adult and, more recently, is implicated in the expression of altered phenotypes of future generations. Some phenotypes, such as fertility, bone strength, and adiposity are highly relevant to food animal production and in utero factors that impinge on those traits are vital to understand. A key systemic regulatory hormone is growth hormone (GH), which has a developmental role in virtually all tissues and organs. This review catalogs the impact of GH on tissue programming and how perturbations early in development influence GH function.
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,790
OpenAlex ID: W2062523318
FWCI: 3.277
Cites: 100
Cited by: 29
Related to: 10