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Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides

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Year: 2016
Type: article
Source: Journal of Controlled Release
DOI: 10.1016/j.jconrel.2016.12.005
Authors: Manuela Chiper, Nassera Tounsi, Ryszard Kole, Antoine Kichler, Guy Zuber
Institutions: Centre National de la Recherche Scientifique, Biotechnologie et Signalisation Cellulaire, Université de Strasbourg, Laboratoire d'Innovation Thérapeutique, University of North Carolina at Chapel Hill, Laboratoire de Chémo-biologie synthétique et thérapeutique, Genethon (France)
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Association Française contre les Myopathies, Agence Nationale de la Recherche, Labex, China Scholarship Council
Awards: G185467900, G2250762047, Medalis Drug Discovery Center, G3188687615, Center of Chemistry of Complex System, G3546037520, G7240651115
OpenAlex ID: W2559758252
FWCI: 4.334
Cites: 61
Cited by: 79
Related to: 10
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