Work

Long-term maintenance of human naïve T cells through in situ homeostasis in lymphoid tissue sites

Year: 2016

Type: article

Abstract: Human naïve T cells are maintained in lymph nodes for decades and clonally expand in situ after cessation of thymopoiesis.

Source: Science Immunology

DOI: 10.1126/sciimmunol.aah6506

Authors: Joseph J. C. Thome, Boris Grinshpun, Brahma V. Kumar, Masaru Kubota, Yoshiaki Ohmura, Harvey Lerner, Gregory D. Sempowski, Yufeng Shen, Donna L. Farber

Institutions: Columbia University Irving Medical Center, Duke University

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Aging, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Center for Research Resources

Awards: Development of lung T cell responses in infant respiratory immunity, Longevity and turnover of human naive T cells in lymphoid tissue, Tissue compartmentalization of human lymphocytes, Development of lung T cell responses in infant respiratory immunity, Medical Scientist Training Program, Becton Dickinson LSR II Analytical Flow Cytometer, Regional Biocontainment Laboratory (RBL)

OpenAlex ID: W2560349103

FWCI: 9.098

Cites: 51

Cited by: 161

Related to: 10