Work

HIWI2 rs508485 Polymorphism Is Associated with Non-obstructive Azoospermia in Iranian Patients.

Year: 2017

Type: article

Abstract: BACKGROUND: gene rs508485 polymorphism and non-obstructive azoospermia. METHODS: rs508485 (T>C) polymorphism using Tetra-ARMS PCR. The presence of eight sequence-tagged site (STS) markers from the Y chromosome AZF region was also investigated by Multiplex PCR (M-PCR). RESULTS: of 0.035 and odds ratio of 2.00 (CI 95%: 1.04-3.86). CONCLUSIONS: gene involved in the piRNA pathway and idiopathic non-obstructive azoospermia in Iranian patients. Therefore, piRNA pathway gene variants can be considered as risk factors for male infertility.

Source: PubMed

Authors: Zeeba Kamaliyan, Sara Pouriamanesh, Mona Amin-Beidokhti, Amir Rezagholizadeh, Reza Mirfakhraie

Institutions: Shahid Beheshti University, Shahid Beheshti University of Medical Sciences, Islamic Azad University, East Tehran Branch

Language: English

Topic: Sperm and Testicular Function

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2560415355

FWCI: 1.317

Cites: 19

Cited by: 17

Related to: 10