Work

Visceral metastatic angiosarcoma treated effectively with oral cyclophosphamide combined with propranolol

Year: 2016

Type: article

Abstract: Angiosarcoma is rare soft tissue sarcoma of endothelial cell origin occurring mainly in white elderly people.1 The most common clinical location is the head and neck. Only a few chemotherapeutic drugs are available for the therapy of metastatic angiosarcoma, with poor results and bad tolerance: paclitaxel or doxorubicin (with a progression-free survival of 3.7 to 5.4 months for nonresectable angiosarcomas treated with doxorubicin2). Cyclophosphamide is safe and easy to use in elderly patients with metastatic angiosarcoma but is of low efficacy used alone.

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2016.10.005