Work

Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

Year: 2016

Type: article

Source: Nature

DOI: 10.1038/nature20605

Authors: Yi Zheng, Ling Qin, Natalia V. Ortiz Zacarías, Henk de Vries, Gye Won Han, Martin Gustavsson, Marta Dabros, Chunxia Zhao, Robert J. Cherney, Percy Carter, Dean Stamos, Ruben Abagyan, Vadim Cherezov, Raymond C. Stevens, Adriaan P. IJzerman, Laura H. Heitman, Andrew Tebben, Irina Kufareva, Tracy M. Handel

Institutions: University of California San Diego, Leiden University, University of Southern California, Bristol-Myers Squibb (United States), Vertex Pharmaceuticals (United States)

Language: English

Topic: Chemokine receptors and signaling

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Chemokine interaction with CXCR4 and ACKR3: structure and activation mechanisms, The structural plasticity of chemokine and gp120 recognition by CCR5, Flexible Macromolecular Docking, Structure Determination of the Chemokine Receptor CCR2 with Novel Inhibitors, Dissecting the interactions of gp120 with chemokine receptor CXCR4, Structure, Dynamics and Activation Mechanisms of Chemokine Receptors, GPCR Network

OpenAlex ID: W2560722699

FWCI: 17.39

Cites: 43

Cited by: 297

Related to: 10