Work

270. Nanoparticle-Mediated Rhodopsin cDNA But Not the Intron-Containing DNA Delivery Causes Transgene Silencing in a Rhodopsin Knockout Model

Year: 2015

Type: article

Abstract: Gene expression is moderated by a multitude of patterns. The cross-talk between the native promoters and all the non-coding endogenous elements, such as transcription factors, enhancers and introns, are tightly controlled in a precise and real-time manner.

Source: Molecular Therapy

DOI: 10.1016/s1525-0016(16)33879-5

Authors: Zongchao Han, Min Zheng, Rajendra Mitra

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

OpenAlex ID: W2561091372

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