Work

Disseminated Cryptococcosis With Brain Involvement in Patients With Chronic Lymphoid Malignancies on Ibrutinib

Year: 2016

Type: article

Abstract: We report 2 cases of disseminated cryptococcosis with central nervous system involvement in patients with chronic lymphoid malignancies occurring within 1 month of starting on ibrutinib. Characteristically, in both cases, no inflammation was seen in the cerebrospinal fluid. Central nervous system mycoses should be considered as a potential complication of ibrutinib.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofw261

Authors: Julia A. Messina, Eileen K. Maziarz, Andrej Spec, Dimitrios P. Kontoyiannis, John R. Perfect

Institutions: Duke University, Washington University in St. Louis, The University of Texas MD Anderson Cancer Center

Language: English

Topic: Fungal Infections and Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053