Work

DNA Hypomethylation in Intragenic and Intergenic Enhancer Chromatin of Muscle-Specific Genes Usually Correlates with their Expression.

Year: 2016

Type: article

Abstract: 's super-enhancer and demonstrated its repression by methylation of its three CG dinucleotides. Our study suggests that DNA hypomethylation increases enhancer tissue-specificity and that SkM super-enhancers sometimes are poised for physiologically important, rapid up-regulation.

Source: Europe PMC (PubMed Central)

Authors: Kenneth C Ehrlich, Heather L Paterson, Michelle Lacey, Melanie Ehrlich

Institution: Tulane University

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Mentoring a Cancer Genetics Program

OpenAlex ID: W2563064533

FWCI: 1.569

Cites: 75

Cited by: 28

Related to: 10