Work

Revisiting the neuropsychiatry of Huntington's disease

Year: 2016

Type: article

Abstract: Huntington's disease (HD) is an autosomal dominant neurodegenerative disease classified under the choreas. Besides motor symptoms, HD is marked by cognitive and behavioral symptoms, impacting patients' functional capacity. The progression of cognitive impairment and neuropsychiatric symptoms occur in parallel with neurodegeneration. The nature of these symptoms is very dynamic, and the major clinical challenges include executive dysfunction, apathy, depression and irritability. Herein, we provide a focused updated review on the cognitive and psychiatric features of HD.

Source: Dementia & Neuropsychologia

DOI: 10.1590/s1980-5764-2016dn1004002

Authors: Antonio Lucio Teixeira, Leonardo Cruz de Souza, Natalia Pessoa Rocha, Erin Furr-Stimming, Edward C. Lauterbach

Institutions: Universidade Federal de Minas Gerais, The University of Texas Health Science Center at Houston, Mercer University, Mercer University Health Sciences Center

Language: English

Topic: Genetic Neurodegenerative Diseases

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2563952227