Work

The Impact of Antibiotic Consumption on Development of Acinetobacter Baumannii Resistance

Year: 2016

Type: article

Abstract: AIM: The aim of this study was to examine the impact of antibiotic consumption on development of antimicrobial resistance in Acinetobacter baumannii. MATERIAL AND METHODS: 2012. Isolates were detected from different clinical samples including urine, wound swab, blood, bronchial aspirate and other samples which were collected from patients situated on various hospital wards. Clinical isolates belonged to one per patient in a given period of time. RESULTS: Antimicrobial resistance was interpreted according to CLSI breakpoints. Consumption of antibiotics was analyzed according to recommendations of the ESAC-Net and current Acinetobacter baumannii classification. Pearson's correlation showed a positive correlation between gentamicin consumption and emerging of resistance (p = 0.023). CONCLUSION: Increase in the antimicrobial use was followed with an increase in resistance of Acinetobacter baumannii isolates. Monitoring of antibiotic resistance and consumption is of a great importance in order to reduce the emergence and spread of antimicrobial resistant organisms in the health care settings.

Source: Materia Socio Medica

DOI: 10.5455/msm.2016.28.449-453

Authors: Djana Granov, Amela Ljubovic, Svjetlana Zec, Nermin Granov, Mirsada Hukic

Institutions: Clinical Center University of Sarajevo, University of Sarajevo, Institute for Biomedical Diagnostics and Research NALAZ, International Burch University

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: NIH Clinical Center