Meningitis, Abscess, and Encephalitis
Year: 2000
Type: book-chapter
Abstract: Leptomeningitis (pachymeningitis, meningitis) is an 1 inflammatory condition involving the leptomeningeal coverings of the brain and spinal cord. The process may be suppurative or nonsuppurative, depending upon the causative organism. Clinically, patients present with fever, headaches, nausea, vomiting, neck stiffness, photophobia, and confusion. The number of routes by which organisms reach the leptomeninges and cause meningitis are several and include hematogeneous dissemination, direct implantation due to surgery or trauma, local extension from an adjacent site, structural abnormalities such as neural tube defects, and retrograde ascending infection (usually via the peripheral nervous system as in rabies).
Source: Humana Press eBooks
Authors: Richard A. Prayson, Mark L. Cohen
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W25652774
