Work

Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response

Year: 2016

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2016.11.031

Authors: Robert Heler, Addison V. Wright, Marija Vucelja, David Bikard, Jennifer A. Doudna, Luciano A. Marraffini

Institutions: Rockefeller University, University of California, Berkeley, University of Virginia, Howard Hughes Medical Institute, Lawrence Berkeley National Laboratory, Innovative Genomics Institute

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, Howard Hughes Medical Institute, Irma T. Hirschl Trust, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Award: Using CRISPR immunity to prevent the spread of virulence traits among pathogens

OpenAlex ID: W2565284095

FWCI: 3.986

Cites: 30

Cited by: 59

Related to: 10