The Investigating of Photoplethysmogram Waveform Amplitude Changes: Aging and Atherosclerosis
Year: 2016
Type: article
Study design: Observational Study
Abstract: This paper focuses on the analysis of PPG waveform amplitude changes. As PPG signal reflects blood volume changes, studying its (peaks and valleys) amplitudes changes is highly appreciated. The results showed a strong positive relationship between age and RI index (R square = 0.657) and a strongly negative relationship between age and systolic peak index (R square = -0.651). The obtained results underline the importance of studying PPG's (peaks and valleys) amplitude changes and their association with age and atherosclerosis. The association between aging, atherosclerosis, arterial stiffness and PPG's morphology can provide a fruitful tool towards disease prevention and early-risk prediction. The increment of systolic peak as we age might indicate the present of atherosclerosis and the start of arterial stiffness. In addition, the increment of RI index as we age, may contribute to the process of high-risk atherosclerosis prediction and therefore approaching risk prevention.
Authors: Yousef Qawqzeh, Loai Kayed, Mohammad Mahmood Otoom, Mafawez Alharbi, Fakhri Alam Khan
Institutions: Majmaah University, Institute of Management Sciences Peshawar
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: diamond
Funder: Majmaah University
OpenAlex ID: W2567280004