Work

Disseminated histoplasmosis presenting as diabetic keto-acidosis in an immunocompetent patient

Year: 2017

Type: article

Abstract: Histoplasma capsulatum causes a spectrum of manifestations from asymptomatic to fatal disseminated disease. Disseminated histoplasmosis is mostly seen in endemic areas among immunocompromised patients such as those with AIDS. Here, we present a patient living in a non-endemic area with previously undiagnosed diabetes mellitus, who presented with septic shock and diabetic ketoacidosis (DKA), and was ultimately diagnosed with disseminated histoplasmosis. The patient rapidly recovered on administration of intravenous liposomal amphotericin followed by oral itraconazole. Uncontrolled diabetes may be a risk factor for disseminated or severe histoplasmosis in otherwise immunocompetent patients.

Source: BMJ Case Reports

DOI: 10.1136/bcr-2016-217915

Authors: Negin Niknam, Prashant Malhotra, Angela Kim, Seth Koenig

Institutions: North Shore University Hospital, Nebraska State Historical Society, Long Island Jewish Medical Center

Language: English

Topic: Fungal Infections and Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2568890421