Work

Anti-inflammatory Potentials of Excretory/Secretory (ES) and Somatic Products of Marshallagia marshalli on Allergic Airway Inflammation in BALB/c Mice.

Year: 2016

Type: article

Abstract: BACKGROUND: modulate the development of ovalbumin-induced airway inflammation in a mouse model. METHODS: were analyzed by inflammatory cell infiltration in bronchoalveolar lavage fluid (BALF), pathological changes and IgE response. RESULTS: decreased cellular infiltration into BALF when they were administered during sensitization with allergen. Pathological changes were decreased in helminth-treated group, as demonstrated by reduced inflammatory cell infiltration, goblet cell hyperplasia, epithelial lesion and smooth muscle hypertrophy. However, no significant differences were observed in IgE serum levels, cytokines and eosinophil counts between different groups. CONCLUSION: as a candidate for the treatment of airway inflammation.

Source: PubMed

Authors: Sima Parande Shirvan, Hassan Borji, Ahmadreza Movassaghi, Mohammadreza Khakzad, Hamidreza Farzin, Mohsen Maleki, Alireza Haghparast

Institutions: Ferdowsi University of Mashhad, Islamic Azad University, Mashhad, Razi Vaccine and Serum Research Institute

Language: English

Topic: Asthma and respiratory diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2572121201

FWCI: 0.982

Cites: 48

Cited by: 7

Related to: 10