Work

Genome Sequences of Diverse Human Cytomegalovirus Strains with Utility in Drug Screening and Vaccine Evaluation

Year: 2017

Type: article

Abstract: Cytomegalovirus displays genetic heterogeneity, which has implications for antiviral and vaccine development. Many studies have focused on laboratory isolates that have been extensively adapted for growth on fibroblasts. Here, we report whole-genome sequences for 10 human cytomegalovirus (HCMV) strains that readily grow on ARPE-19 human retinal pigment epithelial cells.

Source: Genome Announcements

DOI: 10.1128/genomea.01433-16

Authors: Kathleen Corcoran, Carly J. Sherrod, Ellen F. Perkowski, Jordan Texier, Fengsheng Li, I-Ming Wang, Michael McVoy, Tong-Ming Fu, Dirk P. Dittmer

Institutions: University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Merck & Co., Inc., Rahway, NJ, USA (United States), Virginia Commonwealth University, Virginia Commonwealth University Medical Center

Language: English

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: U.S. Public Health Service, National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: G1178797104, G3305169571, G5708403807, Viral Oncogenesis, Latency, and Replication

OpenAlex ID: W2572928668

FWCI: 1.112

Cites: 10

Cited by: 10

Related to: 10