Overexpression and gene amplification of EGFR, HER2, and HER3 in biliary tract carcinomas, and the possibility for therapy with the HER2-targeting antibody pertuzumab Toru KawamotoKazunori IshigeMelanie ThomasYoriko Yamashita-Kashima • Sei ShuNobuyuki IshikuraShunichi AriizumiMasakazu Yamamoto •