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FTY720 Restores PP2A Tumor Suppressor Activity in Polycythemia Vera CD34+ Progenitors Through Inhibition of Jak2 V617F- and PI-3Kγ-Dependent SET Serine Phosphorylation and Enhancement of NOS-Dependent PP2A Tyrosine Nitration

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Year: 2011
Type: conference-abstract
Source: Blood
DOI: 10.1182/blood.v118.21.2494.2494
Authors: Joshua J Oaks, A. Mukhopadhyay, Ramasamy Santhanam, S. A Saddoughi, Paolo Neviani, Jason G Harb, Besim Ogretmen, Robert Bittman, Ross L Levine, Alfonso Quintás-Cardama, Guido Marcucci, Danilo Perrotti
Institutions: The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Medical University of South Carolina, MUSC Hollings Cancer Center, City University of New York, Memorial Sloan Kettering Cancer Center, The University of Texas MD Anderson Cancer Center
Language: English

Topic: Myeloproliferative Neoplasms: Diagnosis and Treatment
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W2574433135
Cites:
Cited by: 4
Related to: 10
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