Work

OCT-based full crystalline lens shape change during accommodation in vivo

Year: 2017

Type: article

Abstract: The full shape of the accommodating crystalline lens was estimated using custom three-dimensional (3-D) spectral OCT and image processing algorithms. Automatic segmentation and distortion correction were used to construct 3-D models of the lens region visible through the pupil. The lens peripheral region was estimated with a trained and validated parametric model. Nineteen young eyes were measured at 0-6 D accommodative demands in 1.5 D steps. Lens volume, surface area, diameter, and equatorial plane position were automatically quantified. Lens diameter & surface area correlated negatively and equatorial plane position positively with accommodation response. Lens volume remained constant and surface area decreased with accommodation, indicating that the lens material is incompressible and the capsular bag elastic.

Source: Biomedical Optics Express

DOI: 10.1364/boe.8.000918

Authors: Eduardo Martinez-Enriquez, Pablo Pérez-Merino, Miriam Velasco-Ocana, Susana Marcos

Institutions: Consejo Superior de Investigaciones Científicas, Instituto de Óptica "Daza de Valdés"

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,913

Funders: European Commission, European Research Council