Work

Management of Clostridium difficile Infection.

Year: 2016

Type: article

Abstract: , this length of treatment may be insufficient to lead to cure; however, continuing antibiotics for longer periods of time may unfavorably alter the microbiome, preventing recovery. Treatment with metronidazole has been associated with an increasing failure rate, and the only clear recommended form of metronidazole for treatment of CDI is the intravenous formulation for patients unable to take oral medications. For vancomycin or fidaxomicin treatment of first CDI recurrences, the drug used in the initial bout can be repeated. For second or future recurrences, vancomycin can be given in pulsed or tapered doses. New modalities of treatment, such as bacteriotherapy and immunotherapy, show promise for the treatment of recurrent CDI.

Source: PubMed

Authors: Layth S Al-Jashaami, Herbert L DuPont

Institutions: University of Arizona, Baylor College of Medicine, Kelsey Research Foundation, University of Arizona College of Medicine- Phoenix

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2577581975

FWCI: 2.332

Cites: 88

Cited by: 37

Related to: 10